GLP-1 Receptor Agonist
Semaglutide Calculator
Calculate reconstitution and weekly dosing with the standard tiered progression schedule.
Weekly Dose
0.25
mg per week
Draw Per Dose
10
units
Concentration
2500
mcg/ml
Standard Titration Schedule
| Weeks | Weekly Dose | Purpose |
|---|---|---|
| 1–4 | 0.25 mg | Initial titration |
| 5–8 | 0.5 mg | Dose escalation |
| 9–12 | 1 mg | Therapeutic dose |
| 13–16 | 1.7 mg | Escalation (if needed) |
| 17+ | 2.4 mg | Maximum/maintenance |
* This follows the standard titration protocol. Some may remain at lower doses based on tolerability and response.
How to Use This Calculator
- Select your vial size – Choose the amount of semaglutide in your vial (3mg, 5mg, or 10mg).
- Enter BAC water amount – Input how much bacteriostatic water you'll add. The default of 2ml works well for most vial sizes.
- Select your current week – Choose which phase of the titration schedule you're in. The calculator automatically adjusts the dose based on the standard protocol.
- Read your results – The calculator shows your weekly dose, how many units to draw, and the concentration. Semaglutide is injected once weekly.
About Semaglutide
Semaglutide is a GLP-1 (glucagon-like peptide-1) receptor agonist. It mimics the incretin hormone GLP-1, which is released after eating.
Key effects include:
- Reduces appetite and increases satiety
- Slows gastric emptying
- Improves glycemic control
- May support cardiovascular health
Important Note
Semaglutide is a prescription medication. This calculator is for educational purposes only. Always use under medical supervision and follow your healthcare provider's dosing instructions.
Frequently Asked Questions
Gradual dose increases help minimize gastrointestinal side effects (nausea, vomiting, diarrhea) which are common when starting GLP-1 agonists. Starting low and increasing slowly allows your body to adjust.
Stay at your current dose longer before increasing, or step back to the previous dose. Many people find that side effects improve over time. Contact your healthcare provider if side effects are severe or persistent.
No. Many people achieve their goals at lower doses (1mg or 1.7mg). The goal is to find the lowest effective dose that works for you. Higher doses aren't necessarily better and may increase side effects.