Hormone Pellet Therapy

Pellet Dosing Calculator

Calculate hormone pellet doses, convert from weekly injections, and estimate pellet duration for testosterone and estradiol therapy.

About Hormone Pellets

What are pellets? Small cylinders (about the size of a grain of rice) implanted under the skin that slowly release hormones over 3-6 months.

Common pellet sizes: Testosterone: 75mg, 100mg, 200mg per pellet. Estradiol: 12.5mg, 25mg per pellet.

Injection to Pellet Converter

Convert your weekly injection dose to pellet equivalent

Select your hormone

Your current weekly injection dose

Time between insertions

4

Pellet Recommendation

Total Dose Needed

1600

mg total

Number of Pellets

8

@ 200mg each

Daily Release

14.3

mg per day (avg)

Note: Pellets typically have 70-80% bioavailability, so your provider may adjust the total dose. Individual metabolism varies significantly.

Pellet Count Calculator

Calculate how many pellets you need for a specific dose

Common Pellet Dosing Ranges

Male Testosterone

  • Range: 800-2000 mg total
  • Pellets: 8-12 x 100-200mg
  • Duration: 4-6 months
  • Target: 600-1000 ng/dL

Female Testosterone

  • Range: 75-225 mg total
  • Pellets: 1-3 x 75mg
  • Duration: 3-4 months
  • Target: 50-100 ng/dL

Estradiol

  • Range: 25-150 mg total
  • Pellets: 2-6 x 12.5-25mg
  • Duration: 3-4 months
  • Target: 50-200 pg/mL

* Doses vary significantly by individual. Work with your healthcare provider to determine optimal dosing based on lab results.

Pellets vs. Injections

Factor Pellets Injections
Frequency Every 3-6 months Weekly or bi-weekly
Hormone Levels Steady, minimal peaks/troughs Peaks after injection, troughs before
Convenience In-office procedure, then no maintenance Self-administered at home
Dose Adjustment Must wait until next insertion Can adjust each injection
Cost Higher upfront, lower over time Lower per dose, ongoing

Frequently Asked Questions

Testosterone pellets typically last 3-6 months for men and 3-4 months for women. Duration depends on your metabolism, activity level, weight, and the total dose implanted. Active individuals may metabolize pellets faster.

Common signs include: return of symptoms (fatigue, low libido, mood changes), declining energy levels, and lab work showing decreasing hormone levels. Most providers recommend re-insertion when you start feeling symptoms return or at scheduled intervals.

It's a simple in-office procedure taking about 10-15 minutes. Local anesthetic is applied, a small incision is made (usually in the hip/buttock area), pellets are inserted with a trocar, and the incision is closed with a steri-strip. Most patients return to normal activities within 24-48 hours, avoiding strenuous exercise for about a week.

Technically yes, but it's difficult and not commonly done. This is why starting with a conservative dose is important, especially for first-time users. Pellets can be partially removed within the first few weeks if necessary, but become harder to locate as they dissolve over time.