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TB-500 Dosage Calculator: Complete Guide to Calculating Your Dose

For educational purposes only. Not medical advice. Full disclaimer
RP
Ryan Peters, PharmD Updated February 2026

Calculating the correct TB-500 dosage requires understanding reconstitution math, typical protocol phases, and how to measure accurate doses with an insulin syringe. This guide walks you through every step of TB-500 dosing calculation.

TB-500 Dosage Calculator: Quick Reference

Use this quick reference to calculate your TB-500 doses based on common reconstitution volumes:

TB-500 Vial SizeBAC Water AddedConcentration2mg Dose2.5mg Dose
5mg1ml5mg/ml40 units (0.4ml)50 units (0.5ml)
5mg2ml2.5mg/ml80 units (0.8ml)100 units (1ml)
10mg2ml5mg/ml40 units (0.4ml)50 units (0.5ml)
10mg4ml2.5mg/ml80 units (0.8ml)100 units (1ml)

Understanding TB-500 Dosing

Standard TB-500 Protocol

TB-500 dosing typically follows a two-phase approach:

Loading Phase (4-6 weeks)
  • Dose: 4-8mg per week
  • Frequency: Split into 2 injections (e.g., 2-2.5mg twice weekly)
  • Purpose: Build up systemic levels for tissue repair
Maintenance Phase (ongoing)
  • Dose: 2-4mg per week
  • Frequency: 1-2 injections weekly
  • Purpose: Maintain healing benefits

Step-by-Step: How to Calculate Your TB-500 Dose

1 Determine Your Reconstitution Volume

First, decide how much bacteriostatic water to add to your TB-500 vial. The amount you add determines the concentration:

Formula: Concentration = Peptide Amount ÷ Water Volume

For a 5mg vial:

  • Add 1ml BAC water → 5mg/ml concentration
  • Add 2ml BAC water → 2.5mg/ml concentration
  • Add 2.5ml BAC water → 2mg/ml concentration

Pro Tip: Using 2ml of BAC water for a 5mg vial creates an easy 2.5mg/ml concentration, making dose calculations simpler.

2 Calculate Units Per Dose

Using a standard U-100 insulin syringe (100 units = 1ml), calculate how many units equal your desired dose:

Formula: Units to inject = (Desired dose ÷ Concentration) × 100

Example: You want 2.5mg from a 5mg vial reconstituted with 2ml BAC water:

  • Concentration = 5mg ÷ 2ml = 2.5mg/ml
  • Units = (2.5mg ÷ 2.5mg/ml) × 100 = 100 units (1ml)

3 Verify Your Math

Always double-check by working backwards:

  • 100 units = 1ml
  • 1ml × 2.5mg/ml = 2.5mg ✓

TB-500 Dosage by Body Weight

Some protocols adjust TB-500 dosing based on body weight:

Body WeightLoading Dose (weekly)Maintenance Dose (weekly)
Under 150 lbs (68kg)4-5mg2mg
150-200 lbs (68-90kg)5-6mg2-2.5mg
Over 200 lbs (90kg)6-8mg2.5-4mg

Common TB-500 Dosing Scenarios

Scenario 1: Standard Loading Protocol

Goal: 5mg per week, split into 2 doses of 2.5mg

Setup: 5mg vial + 2ml BAC water = 2.5mg/ml

Each injection: 100 units (1ml) = 2.5mg

Schedule: Monday and Thursday

Scenario 2: Conservative Protocol

Goal: 4mg per week, split into 2 doses of 2mg

Setup: 5mg vial + 2.5ml BAC water = 2mg/ml

Each injection: 100 units (1ml) = 2mg

Schedule: Monday and Thursday

Scenario 3: High-Dose Loading

Goal: 7.5mg per week, 2.5mg three times weekly

Setup: 10mg vial + 4ml BAC water = 2.5mg/ml

Each injection: 100 units (1ml) = 2.5mg

Schedule: Monday, Wednesday, Friday

TB-500 Reconstitution Tips

Safety Warning: Always use bacteriostatic water (not sterile water) for TB-500 reconstitution. BAC water contains a preservative that allows multi-dose use over several weeks.

  • Add water slowly - Direct the stream against the vial wall, not directly onto the powder
  • Don't shake - Gently swirl until dissolved (usually 1-2 minutes)
  • Store properly - Refrigerate after reconstitution (2-8°C / 36-46°F)
  • Use within 4 weeks - TB-500 stability decreases over time once reconstituted

Frequently Asked Questions

How do I calculate TB-500 dosage?

To calculate TB-500 dosage: First, determine your concentration by dividing the vial size by the amount of BAC water added (e.g., 5mg ÷ 2ml = 2.5mg/ml). Then calculate units to inject using the formula: (desired dose ÷ concentration) × 100. For example, to get 2.5mg from a 2.5mg/ml solution, you would inject 100 units (1ml).

What is the standard TB-500 dose?

The standard TB-500 protocol uses 4-8mg per week during a loading phase (4-6 weeks), typically split into two injections of 2-2.5mg each. After loading, maintenance dosing drops to 2-4mg per week. Most users inject twice weekly on a consistent schedule like Monday/Thursday.

How much bacteriostatic water should I add to TB-500?

For a 5mg TB-500 vial, adding 2ml of bacteriostatic water creates a convenient 2.5mg/ml concentration. For a 10mg vial, 4ml of BAC water gives the same concentration. The exact amount is flexible - more water means a lower concentration and larger injection volumes, while less water means higher concentration and smaller volumes.

How many doses are in a TB-500 vial?

The number of doses depends on your vial size and dose amount. A 5mg vial provides two 2.5mg doses, or two-and-a-half 2mg doses. A 10mg vial provides four 2.5mg doses or five 2mg doses. Most users need 2-3 vials for a standard 4-week loading phase at 5mg/week.

TB-500 Dosage Calculator Summary

Accurate TB-500 dosing comes down to simple math: know your concentration, calculate your units, and maintain a consistent schedule. Use the formulas and reference tables in this guide to ensure you're measuring precisely every time.

For best results, pair proper dosing with correct storage (refrigerated) and administration technique (subcutaneous injection, rotating sites).