BPC-157 (Body Protection Compound-157) is a synthetic peptide derived from a protein found in human gastric juice. It is one of the most commonly used peptides in healing and recovery research. Unlike peptides with complex titration schedules, BPC-157 dosing is relatively straightforward — but choosing the right dose, injection method, and protocol length still matters.
Standard Dose Ranges
BPC-157 dosing in research protocols is typically based on body weight, but most practical guides simplify it to a flat dose range:
| Protocol | Dose Per Injection | Frequency | Duration |
|---|---|---|---|
| Standard healing | 250 mcg | 1-2x daily | 4-6 weeks |
| Moderate injury | 500 mcg | 1x daily | 4-8 weeks |
| Aggressive protocol | 500 mcg | 2x daily | 4-6 weeks |
| Gut healing | 250-500 mcg | 1-2x daily | 6-8 weeks |
The most common starting protocol is 250 mcg twice daily, which totals 500 mcg per day. This balances effectiveness with conservative dosing.
Weight-Based Dosing
Research literature often references doses in mcg per kg of body weight. The commonly cited range is:
For practical purposes:
- A 70 kg (154 lb) person at 3.5 mcg/kg = approximately 250 mcg per dose
- A 90 kg (198 lb) person at 3.5 mcg/kg = approximately 315 mcg per dose
- Most people round to the nearest 50 mcg for easier syringe measurement
Reconstitution Math
BPC-157 is most commonly sold in 5mg vials. Here is how to calculate your concentration and syringe units:
5mg Vial + 2mL Bacteriostatic Water (Recommended)
- Concentration: 5,000 mcg / 2 mL = 2,500 mcg per mL
- Per syringe unit: 2,500 / 100 = 25 mcg per unit
- For 250 mcg dose: 250 / 25 = 10 units
- For 500 mcg dose: 500 / 25 = 20 units
At this concentration, a 5mg vial provides 20 doses at 250 mcg — enough for 10 days at twice-daily dosing, or 20 days at once daily.
5mg Vial + 1mL Bacteriostatic Water
- Concentration: 5,000 mcg per mL
- Per syringe unit: 50 mcg per unit
- For 250 mcg dose: 5 units
- For 500 mcg dose: 10 units
More concentrated means smaller injection volume, but the dose falls on tighter syringe lines. Use a 0.3mL (30 unit) syringe for better precision at low unit counts.
Subcutaneous vs. Intramuscular Injection
BPC-157 can be administered either subcutaneously (under the skin) or intramuscularly (into the muscle). The choice depends on the injury location:
- Subcutaneous (most common): Inject into the belly fat or as close to the injury site as practical. Easiest method, least painful, and effective for most applications
- Intramuscular: Used when the injury is in a specific muscle. Delivers the peptide directly to the target tissue. Requires a slightly longer needle (typically 25-27 gauge, 1 inch)
- Near the injury site: Research suggests that injecting close to the affected area may provide better localized healing, though systemic effects occur regardless of injection location
Vial Planning for a Full Protocol
Plan your vial purchases before starting so you do not run out mid-protocol:
| Protocol | Daily Use | Weeks | Total Needed | 5mg Vials |
|---|---|---|---|---|
| 250mcg 1x/day | 250 mcg | 4 | 7 mg | 2 |
| 250mcg 2x/day | 500 mcg | 4 | 14 mg | 3 |
| 500mcg 1x/day | 500 mcg | 6 | 21 mg | 5 |
| 500mcg 2x/day | 1,000 mcg | 4 | 28 mg | 6 |
Stacking With TB-500
BPC-157 is frequently combined with TB-500 in healing protocols. The two compounds use different mechanisms — BPC-157 modulates growth factors locally while TB-500 promotes systemic cell migration and repair. They are dosed independently and should be reconstituted in separate vials.
A common combination protocol is BPC-157 at 250 mcg twice daily alongside TB-500 at 2.5 mg twice weekly. See our TB-500 calculator for the dosing math on that compound.
Storage and Stability
Unreconstituted BPC-157 powder is stable at room temperature for months, but refrigeration extends shelf life. Once reconstituted with bacteriostatic water, store in the refrigerator and use within 3-4 weeks. Never freeze a reconstituted vial.
Get your exact syringe units for any BPC-157 vial and dose combination with our BPC-157 dosage calculator.